Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 3/20 | 0.78 |
| ▸ | CD40LG | P29965 | 3/20 | 0.78 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22531352 | 1.00 | CD40 (0.78) | CD40CD40LGPTPN1HSD17B10PLAU | |
| SCHEMBL24516452 | 0.89 | CD40 (0.62) | CD40CD40LGPTPN1HSD17B10PLAU | |
| SCHEMBL19020632 | 0.88 | CD40 (1.00) | CD40CD40LGPTPN1HSD17B10PLAU | |
| SCHEMBL22545501 | 0.83 | CD40 (0.65) | CD40CD40LGPTPN1HSD17B10PLAU | |
| SCHEMBL19020634 | 0.75 | CD40 (0.77) | CD40CD40LGPTPN1MEN1KMT2A | |
| SCHEMBL22545564 | 0.71 | PTPN1 (0.61) | CD40CD40LGPTPN1MEN1KMT2A | |
| SCHEMBL20590980 | 0.71 | CD40 (1.00) | CD40CD40LGMEN1KMT2ALMNA | |
| SCHEMBL22223650 | 0.71 | PTPN1 (0.94) | PTPN1PLAUMEN1KMT2AHTT | |
| SCHEMBL2835618 | 0.71 | PTPN1 (0.94) | PTPN1PLAUMEN1KMT2AHTT | |
| SCHEMBL29611669 | 0.71 | PTPN1 (0.94) | PTPN1PLAUMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3952853-A1 | INHIBITORS OF CD40-CD154 BINDING | Tonix Pharmaceuticals Holding Corp. (US) | 2022-02-16 | — | — | EP | disclosed |