Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22828480 | 1.00 | ADORA2A (0.43) | ADORA2AADORA1KDM1APDE4BPDE4A | |
| SCHEMBL19867253 | 0.81 | HTT (0.45) | ADORA2AADORA1PDE4BPDE4APDE4C | |
| SCHEMBL1284289 | 0.80 | PDE4B (0.58) | ADORA2AADORA1PDE4BPDE4APDE4C | |
| SCHEMBL19867182 | 0.78 | ALK (0.46) | ADORA2AADORA1PDE4BPDE4APDE4C | |
| SCHEMBL25637824 | 0.78 | PTK2 (0.54) | ADORA2AADORA1PDE4BPDE4APDE4C | |
| SCHEMBL1283919 | 0.75 | ADORA2A (0.47) | ADORA2AADORA1PDE4BPDE4APDE4C | |
| SCHEMBL24379260 | 0.74 | ALK (0.41) | ADORA2AADORA1PDE4BPDE4APDE4C | |
| SCHEMBL30104177 | 0.73 | SLC22A12 (0.61) | ADORA2AADORA1PDE4BPDE4APDE4C | |
| SCHEMBL30748848 | 0.72 | HTT (0.61) | ADORA2AADORA1PDE4BPDE4APDE4C | |
| SCHEMBL24174509 | 0.72 | HTT (0.61) | ADORA2AADORA1PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12365664-B2 | Small molecule inhibitors of SRC tyrosine kinase | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-07-22 | — | — | US | disclosed |
| US-20220267294-A1 | SMALL MOLECULE INHIBITORS OF SRC TYROSINE KINASE | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2022-08-25 | — | — | US | disclosed |
| EP-3986411-A1 | SMALL MOLECULE INHIBITORS OF SRC TYROSINE KINASE | Dana-Farber Cancer Institute, Inc. (US) | 2022-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12365664-B2 | Small molecule inhibitors of SRC tyrosine kinase | SRC, CTTN, LCK | ADORA2A 4690/4885ADORA1 4785/4885KDM1A 2446/4885 |
| US-20220267294-A1 | SMALL MOLECULE INHIBITORS OF SRC TYROSINE KINASE | SRC, CTTN, LCK | ADORA2A 4690/4885ADORA1 4785/4885KDM1A 2446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.