Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 20/20 | 0.67 |
| ▸ | GRIN2B | Q13224 | 20/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22802831 | 1.00 | GRIN1 (0.67) | GRIN1GRIN2BCYP2C9CYP2C19KCNH2 | |
| SCHEMBL29550108 | 0.92 | GRIN2B (0.73) | GRIN1GRIN2BCYP2C9CYP2C19KCNH2 | |
| SCHEMBL22775465 | 0.92 | GRIN2B (0.73) | GRIN1GRIN2BCYP2C9CYP2C19KCNH2 | |
| SCHEMBL22802721 | 0.90 | GRIN2B (0.68) | GRIN1GRIN2BCYP2C9CYP2C19KCNH2 | |
| SCHEMBL29550337 | 0.90 | GRIN2B (0.68) | GRIN1GRIN2BCYP2C9CYP2C19KCNH2 | |
| SCHEMBL22775267 | 0.89 | GRIN2B (0.69) | GRIN1GRIN2BCYP2C9CYP2C19KCNH2 | |
| SCHEMBL29550743 | 0.89 | GRIN2B (0.69) | GRIN1GRIN2BCYP2C9CYP2C19KCNH2 | |
| SCHEMBL22775445 | 0.88 | GRIN1 (0.61) | GRIN1GRIN2BCYP2C9CYP2C19KCNH2 | |
| SCHEMBL29550431 | 0.88 | GRIN1 (0.61) | GRIN1GRIN2BCYP2C9CYP2C19KCNH2 | |
| SCHEMBL22775113 | 0.84 | GRIN1 (0.64) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983075-A1 | SUBSTITUTED PYRAZOLO-PYRIDINE AMIDES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | disclosed |