Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 12/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955232 | 1.00 | KDM4E (0.62) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL31680366 | 0.90 | KDM4E (0.55) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL2945448 | 0.89 | MAPT (0.52) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL10098916 | 0.88 | MAPT (0.46) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL2735112 | 0.86 | KDM4E (0.83) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL27988352 | 0.85 | KDM4E (0.85) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL14549133 | 0.85 | MAPT (0.49) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL13236626 | 0.85 | KDM4E (0.58) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL3123317 | 0.80 | KDM4E (0.74) | KDM4EHPGDHTTMAPTLMNA | |
| SCHEMBL3123320 | 0.80 | KDM4E (0.74) | KDM4EHPGDHTTMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759043-B2 | Oxime ester photoinitiators | CIBA SPECIALTY CHEMICALS CORP. (US) | 2010-07-20 | — | — | US | disclosed |
| US-20080096115-A1 | Oxime Ester Photoinitiators | CIBA SPECIALTY CHEMICALS CORP. | 2008-04-24 | — | — | US | disclosed |
| EP-1778636-B1 | OXIME ESTER PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-12-19 | — | — | EP | disclosed |
| EP-1778636-A1 | OXIME ESTER PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006018405-A1 | OXIME ESTER PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096115-A1 | Oxime Ester Photoinitiators | NR2E3, CBR3, AHR | KDM4E 989/4885HPGD 1649/4885HTT 3450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.