Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 17/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960465 | 0.92 | SSTR5 (0.55) | SSTR5MEN1KMT2AKCNH2MCHR1 | |
| SCHEMBL2957255 | 0.88 | SSTR5 (0.68) | SSTR5MEN1KMT2AKCNH2MCHR1 | |
| SCHEMBL2954268 | 0.86 | MCHR1 (0.58) | SSTR5MEN1KMT2AKCNH2MCHR1 | |
| SCHEMBL2960124 | 0.84 | KMT2A (0.52) | SSTR5KMT2AKCNH2MCHR1 | |
| SCHEMBL2957297 | 0.84 | SSTR5 (0.52) | SSTR5MEN1KMT2AKCNH2 | |
| SCHEMBL2957160 | 0.83 | SSTR5 (0.71) | SSTR5KCNH2 | |
| SCHEMBL2964426 | 0.82 | SSTR5 (0.59) | SSTR5KCNH2MCHR1 | |
| SCHEMBL2964548 | 0.82 | SSTR5 (0.53) | SSTR5KCNH2MCHR1 | |
| SCHEMBL2951159 | 0.82 | SSTR5 (0.68) | SSTR5KCNH2 | |
| SCHEMBL2957931 | 0.82 | MCHR1 (0.57) | SSTR5MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772253-B2 | Amide derivatives as somatostatin receptor 5 antagonists | HOFFMAN-LA ROCHE INC. (US) | 2010-08-10 | — | — | US | disclosed |
| EP-1893603-B1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2009-10-14 | — | — | EP | disclosed |
| US-20060276508-A1 | Amide derivatives as somatostatin receptor 5 antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276508-A1 | Amide derivatives as somatostatin receptor 5 antagonists | SSTR5, SSTR3, SSTR1 | SSTR5 1/4885MEN1 528/4885KMT2A 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.