SCHEMBL29555145

SCHEMBL29555145

COC(=O)c1ccc(COc2cccc(C3CCN(C(=O)O)CC3)n2)cc1F

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24330447 0.89 PRMT5 (0.46) GLP1R
SCHEMBL24329298 0.86 GLP1R (0.46) GLP1R
SCHEMBL29555212 0.82 PRMT5 (0.49) GLP1R
SCHEMBL24329756 0.82 PRMT5 (0.49) GLP1R
SCHEMBL25339172 0.82 GLP1R (0.54) GLP1R
SCHEMBL29554959 0.80 PRMT5 (0.47) GLP1R
SCHEMBL24329241 0.80 PRMT5 (0.47) GLP1R
SCHEMBL29555528 0.79 GLP1R (0.51) GLP1R
SCHEMBL29555176 0.79 GLP1R (0.53) GLP1R
SCHEMBL24329305 0.78 PRMT5 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022078152-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF 杭州中美华东制药有限公司 2022-04-21 WO disclosed