Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.42 |
| ▸ | NPY1R | P25929 | 9/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.42 |
| ▸ | NPY2R | P49146 | 5/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630523 | 0.95 | NPY4R (0.40) | NPY4RNPY1RNPY5RNPY2RPTGS1 | |
| SCHEMBL30676230 | 0.94 | NPY4R (0.41) | NPY4RNPY1RNPY5RNPY2RPTGS1 | |
| SCHEMBL3505407 | 0.92 | NPY4R (0.48) | NPY4RNPY1RNPY5RNPY2RPTGS1 | |
| SCHEMBL30193470 | 0.91 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RPTGS1 | |
| SCHEMBL29630413 | 0.91 | PTGS1 (0.43) | NPY4RNPY1RNPY5RNPY2RPTGS1 | |
| SCHEMBL14027228 | 0.91 | NPY4R (0.40) | NPY4RNPY1RNPY5RNPY2RPTGS1 | |
| SCHEMBL30929978 | 0.91 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2RPTGS1 | |
| SCHEMBL29412493 | 0.91 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2RPTGS1 | |
| SCHEMBL30148051 | 0.91 | NPY4R (0.50) | NPY4RNPY1RNPY5RNPY2RPTGS1 | |
| SCHEMBL30544344 | 0.89 | NPY4R (0.42) | NPY4RNPY1RNPY5RNPY2RPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789180-B | KIF 13B-derived peptides and methods of inhibiting angiogenesis | 伊利诺伊大学理事会 | 2023-09-08 | — | — | CN | disclosed |
| US-11299524-B2 | KIF13B-derived peptide and method of inhibiting angiogenesis | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-04-12 | — | — | US | disclosed |