Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556248 | 0.96 | MAPT (0.61) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL29556074 | 0.96 | MAPT (0.61) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL29555992 | 0.96 | MEN1 (0.56) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL29555934 | 0.94 | MEN1 (0.58) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL29555965 | 0.88 | MEN1 (0.53) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL29556273 | 0.88 | MEN1 (0.51) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL15786287 | 0.87 | MEN1 (0.76) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL27193045 | 0.87 | MAPK14 (0.54) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL29556382 | 0.84 | MEN1 (0.51) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL29556215 | 0.84 | MEN1 (0.67) | MEN1KMT2AMAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |