Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497262 | 0.80 | FGFR1 (0.47) | FGFR1TBXA2RPLA2G4AF2F10 | |
| SCHEMBL30497324 | 0.79 | FGFR1 (0.54) | FGFR1TBXA2RF2F10PRSS1 | |
| SCHEMBL30497301 | 0.78 | FGFR1 (0.56) | FGFR1TBXA2RPLA2G4AF2F10 | |
| SCHEMBL1608848 | 0.78 | CYP11B1 (0.60) | FGFR1F2F10PRSS1MEN1 | |
| SCHEMBL30497328 | 0.78 | FGFR1 (0.47) | FGFR1TBXA2RPLA2G4AF2F10 | |
| SCHEMBL30497306 | 0.78 | FGFR1 (0.47) | FGFR1TBXA2RPLA2G4AF2F10 | |
| SCHEMBL29555468 | 0.77 | FGFR1 (0.46) | FGFR1TBXA2RPLA2G4AF2F10 | |
| SCHEMBL3838757 | 0.76 | FGFR1 (0.56) | FGFR1TBXA2RPLA2G4AF2F10 | |
| SCHEMBL13508660 | 0.75 | CYP11B1 (0.57) | FGFR1TBXA2RPLA2G4AMEN1TP53 | |
| SCHEMBL29555429 | 0.75 | FGFR1 (0.47) | FGFR1TBXA2RPLA2G4AF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3972596-A1 | COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES | Pfizer Inc. (US) | 2022-03-30 | — | — | EP | claimed |
| EP-4598908-A1 | HSD17B13 INHIBITORS AND/OR DEGRADERS | Pfizer Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| EP-4373821-A1 | GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF | Hepagene Therapeutics (HK) Limited (HK) | 2024-05-29 | — | — | EP | disclosed |
| WO-2024075051-A1 | HSD17B13 INHIBITORS AND/OR DEGRADERS | PFIZER INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| CN-117715906-A | Glucagon-like peptide-1 receptor modulators and uses thereof | 和博医药有限公司 | 2024-03-15 | — | — | CN | disclosed |
| WO-2023001237-A1 | GLUCAGON-LIKE PEPTIDE-1 RECEPTOR MODULATORS AND USES THEREOF | Hepagene Therapeutics (HK) Limited (CN) | 2023-01-26 | — | — | WO | disclosed |
| EP-3972596-A1 | COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES | Pfizer Inc. (US) | 2022-03-30 | — | — | EP | disclosed |