Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.44 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556262 | 0.88 | S1PR2 (0.58) | EPHX2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29555831 | 0.86 | HDAC3 (0.47) | EPHX2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29556809 | 0.86 | EPHX2 (0.53) | EPHX2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29556044 | 0.83 | EPHX2 (0.50) | EPHX2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29556370 | 0.83 | MAPT (0.50) | S1PR2MEN1MAPTKMT2ARAB9A | |
| SCHEMBL29555904 | 0.82 | EPHX2 (0.52) | EPHX2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29556142 | 0.81 | MEN1 (0.62) | EPHX2MEN1MAPTKMT2ARAB9A | |
| SCHEMBL29555858 | 0.81 | MEN1 (0.62) | EPHX2MEN1MAPTKMT2ARAB9A | |
| SCHEMBL29557083 | 0.80 | EPHX2 (0.49) | EPHX2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29556404 | 0.78 | MEN1 (0.51) | S1PR2MEN1MAPTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |