Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555999 | 0.92 | MEN1 (0.72) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL17084253 | 0.89 | MEN1 (0.87) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL29556263 | 0.86 | MAPT (0.69) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL7611935 | 0.85 | MEN1 (0.76) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL19707566 | 0.85 | GAA (0.65) | MEN1KMT2AMAPTKDM4ETRPV1 | |
| SCHEMBL6724512 | 0.84 | MAPT (0.53) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL24756290 | 0.82 | MAPT (0.76) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL23832082 | 0.82 | MEN1 (0.58) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL29555968 | 0.81 | KMT2A (0.74) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL29555918 | 0.81 | MEN1 (0.81) | MEN1KMT2AMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |