SCHEMBL29556162

SCHEMBL29556162

O=C(Nc1cccc(Cl)c1)Nc1cc(Cl)cc(Cl)c1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 12/20 0.89
KMT2A Q03164 12/20 0.89
MAPT P10636 6/20 0.89
LMNA P02545 4/20 0.89
HTT P42858 2/20 0.89
ALDH1A1 P00352 2/20 0.89
RAB9A P51151 8/20 0.79
NPC1 O15118 6/20 0.79
NPSR1 Q6W5P4 1/20 0.76
SMN1; SMN2 Q16637 2/20 0.66
P2RY1 P47900 1/20 0.66
L3MBTL1 Q9Y468 2/20 0.64
TP53 P04637 1/20 0.64
TSHR P16473 1/20 0.64
NFKB1 P19838 1/20 0.64
NFKB2 Q00653 1/20 0.64
RELA Q04206 1/20 0.64
NOX1 Q9Y5S8 1/20 0.64
GRIK1 P39086 1/20 0.62
CA12 O43570 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29077780 1.00 MEN1 (0.89) MEN1KMT2AMAPTLMNAHTT
SCHEMBL2682054 0.94 KMT2A (1.00) MEN1KMT2AMAPTLMNAHTT
SCHEMBL29533340 0.89 MEN1 (1.00) MEN1KMT2AMAPTLMNAHTT
SCHEMBL10344695 0.89 MEN1 (1.00) MEN1KMT2AMAPTLMNAHTT
SCHEMBL29555972 0.88 MEN1 (0.74) MEN1KMT2AMAPTLMNAHTT
SCHEMBL29555917 0.88 MEN1 (0.82) MEN1KMT2AMAPTLMNAHTT
SCHEMBL11049956 0.87 MEN1 (0.85) MEN1KMT2AMAPTLMNAHTT
SCHEMBL12218114 0.86 MEN1 (1.00) MEN1KMT2AMAPTLMNAHTT
SCHEMBL28563388 0.86 MEN1 (0.77) MEN1KMT2AMAPTLMNAHTT
SCHEMBL4740825 0.86 KMT2A (0.77) MEN1KMT2AMAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073736-B Catalytic method for controllable copolymerization of epoxy and isothiocyanate 华南理工大学 2023-08-22 CN claimed
CN-115073736-B Catalytic method for controllable copolymerization of epoxy and isothiocyanate 华南理工大学 2023-08-22 CN disclosed
WO-2022078533-A1 SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) 2022-04-21 WO disclosed