Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555891 | 0.93 | P2RX1 (0.67) | P2RX1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL29556257 | 0.91 | P2RX1 (0.56) | P2RX1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL29555858 | 0.90 | MEN1 (0.62) | P2RX1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL29556142 | 0.90 | MEN1 (0.62) | P2RX1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL29556351 | 0.86 | P2RX1 (0.56) | P2RX1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL29556929 | 0.86 | MAPT (0.50) | P2RX1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL29557086 | 0.84 | MEN1 (0.64) | P2RX1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL29556278 | 0.83 | MAPT (0.60) | P2RX1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL11002886 | 0.83 | MAPT (0.58) | P2RX1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL29556410 | 0.83 | MTOR (0.61) | P2RX1MAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |