SCHEMBL29557461

SCHEMBL29557461

Oc1ccc(-c2ccc(O)cc2F)c(F)c1

nearest known ligand 0.74

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 15/20 0.74
ESR2 Q92731 7/20 0.74
AR P10275 2/20 0.52
HSD17B1 P14061 1/20 0.48
HSD17B2 P37059 1/20 0.48
MAOA P21397 1/20 0.46
UGT1A1 P22309 1/20 0.46
MAOB P27338 1/20 0.46
FGFR1 P11362 1/20 0.46
FGFR2 P21802 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2862424 1.00 ESR1 (0.74) ESR1ESR2ARHSD17B1HSD17B2
SCHEMBL22688379 0.90 ESR1 (0.63) ESR1ESR2ARHSD17B1HSD17B2
SCHEMBL1513816 0.88 ESR1 (0.61) ESR1ESR2ARHSD17B1HSD17B2
SCHEMBL26111049 0.86 ESR1 (0.59) ESR1ESR2ARHSD17B1HSD17B2
SCHEMBL16982126 0.86 ESR1 (0.59) ESR1ESR2ARHSD17B1HSD17B2
SCHEMBL26364228 0.86 ESR1 (0.59) ESR1ESR2ARHSD17B1HSD17B2
SCHEMBL31190145 0.86 ESR1 (1.00) ESR1ESR2ARHSD17B1HSD17B2
SCHEMBL16982140 0.85 ESR1 (0.57) ESR1ESR2ARHSD17B1HSD17B2
SCHEMBL28226426 0.85 ESR1 (0.70) ESR1ESR2HSD17B1HSD17B2FGFR1
SCHEMBL38659424 0.85 ESR1 (0.70) ESR1ESR2HSD17B1HSD17B2FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022239655-A1 RESIN COMPOSITION FOR COATING, POLYMER, METHOD FOR PRODUCING POLYMER, COATING FILM AND METHOD FOR PRODUCING SAME 富士フイルム株式会社 2022-11-17 WO disclosed
WO-2022239656-A1 COATING RESIN COMPOSITION, POLYMER, POLYMER PRODUCTION METHOD, COATING FILM AND PRODUCTION METHOD THEREFOR 富士フイルム株式会社 2022-11-17 WO disclosed