Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 15/20 | 0.70 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28716995 | 1.00 | MAP4K1 (0.70) | MAP4K1ALKEGFRINSRIGF1R | |
| SCHEMBL28717883 | 0.88 | MAP4K1 (0.53) | MAP4K1 | |
| SCHEMBL29557636 | 0.88 | MAP4K1 (0.53) | MAP4K1 | |
| SCHEMBL28723666 | 0.87 | MAP4K1 (0.57) | MAP4K1 | |
| SCHEMBL29557738 | 0.87 | MAP4K1 (0.57) | MAP4K1 | |
| SCHEMBL29558016 | 0.86 | MAP4K1 (0.51) | MAP4K1ALK | |
| SCHEMBL28717557 | 0.86 | MAP4K1 (0.51) | MAP4K1ALK | |
| SCHEMBL28717562 | 0.85 | MAP4K1 (0.72) | MAP4K1 | |
| SCHEMBL29557866 | 0.85 | MAP4K1 (0.72) | MAP4K1 | |
| SCHEMBL28717528 | 0.85 | MAP4K1 (0.72) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315796-A | Compound used as HPK1 kinase inhibitor and preparation method and application thereof | 中国药科大学 | 2022-04-12 | — | — | CN | disclosed |