Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 18/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 18/20 | 0.68 |
| ▸ | PDE4A | P27815 | 3/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.60 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Revizinone SCHEMBL9584593 | 1.00 | PDE3B (0.68) | PDE3BPDE3APDE4APDE4BPDE4C | |
| Revizinone SCHEMBL7297062 | 1.00 | PDE3B (0.68) | PDE3BPDE3APDE4APDE4BPDE4C | |
| Revizinone SCHEMBL7289525 | 1.00 | PDE3B (0.68) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9584441 | 0.91 | PDE3B (0.70) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9584347 | 0.91 | PDE3B (0.72) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9584335 | 0.91 | PDE3B (0.72) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9583358 | 0.91 | PDE3B (0.70) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL9583372 | 0.91 | PDE3B (0.70) | PDE3BPDE3APDE4APDE4BPDE4C | |
| Water SCHEMBL9583851 | 0.90 | PDE3B (0.71) | PDE3BPDE3APDE4APDE4BPDE4C | |
| Water SCHEMBL9583863 | 0.90 | PDE3B (0.71) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220347170-A1 | Method of Reducing Brow Ache | LENZ THERAPEUTICS OPERATIONS, INC. | 2022-11-03 | — | — | US | disclosed |
| WO-2022232205-A1 | A METHOD OF REDUCING BROW ACHE | LENZ THERAPEUTICS, INC. (US) | 2022-11-03 | — | — | WO | disclosed |
| CN-114340631-A | Combination for reducing serum phosphate in a patient | 阿德利克斯股份有限公司 | 2022-04-12 | — | — | CN | disclosed |