Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 18/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28717650 | 0.88 | MAP4K1 (0.60) | MAP4K1ALK | |
| SCHEMBL30921791 | 0.88 | MAP4K1 (0.69) | MAP4K1ALK | |
| SCHEMBL29557964 | 0.88 | MAP4K1 (0.69) | MAP4K1ALK | |
| SCHEMBL29557649 | 0.88 | MAP4K1 (0.60) | MAP4K1ALK | |
| SCHEMBL29557916 | 0.87 | MAP4K1 (0.70) | MAP4K1ALK | |
| SCHEMBL24716379 | 0.87 | MAP4K1 (0.74) | MAP4K1ALK | |
| Methyl Alcohol SCHEMBL28720679 | 0.86 | MAP4K1 (0.67) | MAP4K1ALK | |
| SCHEMBL29558038 | 0.86 | MAP4K1 (0.70) | MAP4K1ALK | |
| SCHEMBL29557531 | 0.86 | MAP4K1 (0.58) | MAP4K1ALK | |
| SCHEMBL28717546 | 0.86 | MAP4K1 (0.58) | MAP4K1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315796-B | Compounds used as HPK1 kinase inhibitor, preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-114315796-A | Compound used as HPK1 kinase inhibitor and preparation method and application thereof | 中国药科大学 | 2022-04-12 | — | — | CN | disclosed |