SCHEMBL29558178

SCHEMBL29558178

O=C(Cl)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.41
TRPA1 O75762 2/20 0.36
TRPV1 Q8NER1 2/20 0.36
MALT1 Q9UDY8 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL590879 1.00 DHODH (0.41) DHODHTRPA1TRPV1MALT1
SCHEMBL29918540 0.89 DHODH (0.41) DHODHTRPA1MALT1
SCHEMBL535475 0.89 DHODH (0.41) DHODHTRPA1MALT1
SCHEMBL29361008 0.89 DHODH (0.41) DHODHTRPA1MALT1
Hydrochloric Acid SCHEMBL23754596 0.88 DHODH (0.41) DHODHTRPA1MALT1
SCHEMBL29563830 0.88 SCN9A (0.41) DHODHTRPA1MALT1
SCHEMBL15774986 0.88 SCN9A (0.41) DHODHTRPA1MALT1
SCHEMBL590438 0.88 DHODH (0.41) DHODHTRPA1TRPV1MALT1
SCHEMBL23249646 0.88 DHODH (0.41) DHODHTRPA1MALT1
SCHEMBL27824025 0.87 DHODH (0.35) DHODHTRPA1TRPV1MALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820295-B Continuous synthesis method and system of 3-bromo-1- (3-chloropyridin-2-yl) -1H-pyrazole-5-formyl chloride 天津凯莱英医药科技发展有限公司 2024-12-20 CN claimed
CN-118666829-A Preparation method of cyano-substituted benzoxazine-4-one derivative 江苏扬农化工股份有限公司 2024-09-20 CN claimed
CN-117820295-A Continuous synthesis method and system of 3-bromo-1- (3-chloropyridin-2-yl) -1H-pyrazole-5-formyl chloride 天津凯莱英医药科技发展有限公司 2024-04-05 CN claimed
CN-117069711-A Preparation method of benzoxazine-4-one derivative 江苏扬农化工股份有限公司 2023-11-17 CN claimed
CN-116724015-A Process for preparing insecticidal anthranilamides UPL有限公司 2023-09-08 CN claimed
CN-116490492-A Solid state form of cyantraniliprole 安道麦马克西姆有限公司 2023-07-25 CN claimed
EP-4165031-A1 SOLID STATE FORMS OF CYANTRANILIPROLE Adama Makhteshim Ltd. (IL) 2023-04-19 EP claimed
CN-115385903-A Preparation method of cyano-substituted benzoxazine-4-one derivative 江苏扬农化工股份有限公司 2022-11-25 CN claimed
WO-2022149098-A1 PROCESS FOR PREPARATION OF INSECTICIDAL ANTHRANILAMIDES UPL LIMITED (IN) 2022-07-14 WO claimed
CN-119775254-A Preparation method of o-carboxamido benzamide compound and intermediate thereof 顺毅股份有限公司 2025-04-08 CN disclosed
CN-117820295-B Continuous synthesis method and system of 3-bromo-1- (3-chloropyridin-2-yl) -1H-pyrazole-5-formyl chloride 天津凯莱英医药科技发展有限公司 2024-12-20 CN disclosed
CN-115057844-B Chlorantraniliprole Process for the preparation of amides 江苏七洲绿色科技研究院有限公司 2024-12-06 CN disclosed
CN-118666829-A Preparation method of cyano-substituted benzoxazine-4-one derivative 江苏扬农化工股份有限公司 2024-09-20 CN disclosed
CN-118666829-A Preparation method of cyano-substituted benzoxazine-4-one derivative 江苏扬农化工股份有限公司 2024-09-20 CN disclosed
CN-114874185-A Method for preparing o-formamido benzamide compound 青岛恒宁生物科技有限公司 2022-08-09 CN disclosed
WO-2022149098-A1 PROCESS FOR PREPARATION OF INSECTICIDAL ANTHRANILAMIDES UPL LIMITED (IN) 2022-07-14 WO disclosed
CN-114716408-A Bisamide derivative containing aromatic amide and preparation method and application thereof 南开大学 2022-07-08 CN disclosed
CN-114516855-A Preparation of pyridylpyrazole amide compounds and intermediates therefor 湖南化工研究院有限公司 2022-05-20 CN disclosed
CN-114516854-A Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof 湖南化工研究院有限公司 2022-05-20 CN disclosed
CN-109988150-B N-alkyl-N-cyanoalkyl benzamide compounds and application thereof 江苏中旗科技股份有限公司 2022-04-12 CN disclosed