SCHEMBL29558259

SCHEMBL29558259

C/C(=C/C(=O)O)C(=O)OC(C)C

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.45
TSHR P16473 2/20 0.44
ADRA1A P35348 1/20 0.35
PDE4D Q08499 1/20 0.35
GAA P10253 3/20 0.35
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
HTT P42858 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
OPRK1 P41145 2/20 0.30
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558956 1.00 HCAR2 (0.45) HCAR2TSHRADRA1APDE4DGAA
SCHEMBL25263596 1.00 HCAR2 (0.45) HCAR2TSHRADRA1APDE4DGAA
SCHEMBL24725723 0.82 HCAR2 (0.45) HCAR2TSHRADRA1APDE4DGAA
SCHEMBL30139621 0.80 HTT (0.32) HCAR2HTT
SCHEMBL10592771 0.79 MAPT (0.33) HCAR2TSHRALDH1A1MAPTKDM1A
SCHEMBL1532594 0.78 TSHR (0.50) HCAR2TSHRADRA1APDE4DGAA
SCHEMBL666918 0.78 TSHR (0.50) HCAR2TSHRADRA1APDE4DGAA
SCHEMBL13613127 0.78 TSHR (0.50) HCAR2TSHRADRA1APDE4DGAA
SCHEMBL28098604 0.77 HCAR2 (0.41) HCAR2TSHRADRA1APDE4DGAA
SCHEMBL4602194 0.77 SLC7A5 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112262189-B Surface conditioner for water-based coating, water-based coating composition, coating film, and multilayer coating film 楠本化成株式会社 2022-05-03 CN disclosed