Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24946534 | 1.00 | KMT2A (0.41) | KMT2AMEN1SMN1; SMN2KDM4ECA12 | |
| SCHEMBL12565526 | 0.82 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2KDM4ECA12 | |
| SCHEMBL3817412 | 0.81 | KMT2A (0.41) | KMT2AMEN1SMN1; SMN2KDM4ECA12 | |
| SCHEMBL30753220 | 0.77 | TSHR (0.39) | KMT2AMEN1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL14126104 | 0.77 | POLB (0.39) | KMT2AMEN1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL30753222 | 0.77 | TSHR (0.39) | KMT2AMEN1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL30753217 | 0.75 | NR4A2 (0.45) | KMT2AMEN1SMN1; SMN2KDM4ENR4A2 | |
| SCHEMBL20509597 | 0.74 | KMT2A (0.41) | KMT2AMEN1SMN1; SMN2KDM4ECA12 | |
| SCHEMBL30753230 | 0.74 | TSHR (0.39) | KMT2AMEN1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL869550 | 0.73 | BRD4 (0.50) | KMT2AMEN1KDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480534-B | Benzimidazole or azabenzimidazole-6-carboxylic acid compounds and application thereof | 广州必贝特医药股份有限公司 | 2022-05-13 | — | — | CN | disclosed |