SCHEMBL29560

SCHEMBL29560

CC(NCc1ccccc1)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.76
CASR P41180 4/20 0.65
POLB P06746 1/20 0.59
SIGMAR1 Q99720 2/20 0.59
CYP3A4 P08684 2/20 0.57
CHRM2 P08172 1/20 0.57
HTR1A P08908 1/20 0.57
ADRA2A P08913 1/20 0.57
ADORA3 P0DMS8 1/20 0.57
CHRM1 P11229 1/20 0.57
SMPD1 P17405 1/20 0.57
DRD1 P21728 1/20 0.57
TBXA2R P21731 1/20 0.57
SLC6A2 P23975 1/20 0.57
SLC6A4 P31645 1/20 0.57
ADRA1A P35348 1/20 0.57
OPRM1 P35372 1/20 0.57
DRD3 P35462 1/20 0.57
HTR2B P41595 1/20 0.57
SLC6A3 Q01959 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL774613 1.00 SMN1; SMN2 (0.76) SMN1; SMN2CASRPOLBSIGMAR1CYP3A4
SCHEMBL79765 1.00 SMN1; SMN2 (0.76) SMN1; SMN2CASRPOLBSIGMAR1CYP3A4
Hydrochloric Acid SCHEMBL27830673 0.98 SMN1; SMN2 (0.79) SMN1; SMN2CASRPOLBSIGMAR1CYP3A4
SCHEMBL27939948 0.98 SMN1; SMN2 (0.73) SMN1; SMN2CASRPOLBSIGMAR1CYP3A4
Hydrochloric Acid SCHEMBL5493749 0.98 SMN1; SMN2 (0.79) SMN1; SMN2CASRPOLBSIGMAR1CYP3A4
Hydrochloric Acid SCHEMBL9635019 0.98 SMN1; SMN2 (0.79) SMN1; SMN2CASRPOLBSIGMAR1CYP3A4
SCHEMBL11881252 0.96 SMN1; SMN2 (0.70) SMN1; SMN2CASRPOLBSIGMAR1CYP3A4
SCHEMBL14469578 0.96 SMN1; SMN2 (0.82) SMN1; SMN2CASRPOLBSIGMAR1CYP3A4
Diethylamine SCHEMBL27544555 0.91 SMN1; SMN2 (0.65) SMN1; SMN2CASRPOLBSIGMAR1CYP3A4
SCHEMBL11877401 0.90 CASR (0.73) SMN1; SMN2CASRPOLBSIGMAR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2489 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3807293-B1 PEPTIDES HAVING INHIBITORY ACTIVITY ON NEURONAL EXOCYTOSIS ACRAF (IT) 2026-01-14 EP claimed
EP-3807294-B1 PEPTIDES HAVING INHIBITORY ACTIVITY ON MUSCARINIC RECEPTOR M3 ACRAF (IT) 2026-01-14 EP claimed
US-12377035-B2 Peptides for inhibiting cholinergic calcitonin gene-related peptide (CGRP) and acetylcholine (ACH) release or inhibiting sensitization-mediated by TRPV1-mediated excitability in sensory neurons and methods of use thereof AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO—A.C.R.A.F. S.p.A. (IT) 2025-08-05 US claimed
EP-4274878-B1 BASIC ASHLESS ADDITIVES AND LUBRICATING COMPOSITIONS CONTAINING SAME LUBRIZOL CORP (US) 2024-12-25 EP claimed
US-12102705-B2 Peptides having inhibitory activity on muscarinic receptor M3 AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO—A.C.R.A.F. S.p.A. (IT) 2024-10-01 US claimed
CN-117886718-B Preparation method of high-selectivity asymmetric urea compound and asymmetric urea compound 内蒙古工业大学 2024-05-24 CN claimed
CN-117886718-A Preparation method of high-selectivity asymmetric urea compound and asymmetric urea compound 内蒙古工业大学 2024-04-16 CN claimed
CN-117383994-A Preparation method of asymmetric urea compound and asymmetric urea compound 内蒙古工业大学 2024-01-12 CN claimed
CN-113330004-B Differential solubility driven asymmetric conversion process for substituted 2H-chromene-3-carboxylic acids 株式会社AskAt 2023-11-17 CN claimed
EP-4274878-A1 BASIC ASHLESS ADDITIVES AND LUBRICATING COMPOSITIONS CONTAINING SAME The Lubrizol Corporation (US) 2023-11-15 EP claimed
EP-0845454-A1 Method for the production of optically active cyclopropane derivatives Ajinomoto Co., Inc. (JP) 1998-06-03 EP claimed
EP-0843682-A1 HIGH PURITY FORMULATIONS OF HIGHLY SUBSTITUTED LITHIUM AMIDE BASES FMC CORPORATION (US) 1998-05-27 EP claimed
US-5726308-A High purity formulations of highly substituted lithium amide bases FMC CORPORATION (US) 1998-03-10 US claimed
WO-1997006173-A1 HIGH PURITY FORMULATIONS OF HIGHLY SUBSTITUTED LITHIUM AMIDE BASES FMC CORPORATION (US) 1997-02-20 WO claimed
WO-1994026708-A1 OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES THE UPJOHN COMPANY (US) 1994-11-24 WO claimed
US-5302604-A Squalene synthetase inhibitors, anticarcinogenic agents, zaragozic acid derivatives MERCK & CO., INC. (US) 1994-04-12 US claimed
US-5294627-A Anticholesterol MERCK & CO., INC. (US) 1994-03-15 US claimed
WO-1993017557-A1 CHOLESTEROL LOWERING COMPOUNDS PRODUCED BY DIRECTED BIOSYNTHESIS MERCK & CO., INC. (US) 1993-09-16 WO claimed
US-4584291-A ANTIBIOTICS AND BETA-LACTAMASE INHIBITORS BEECHAM GROUP P.L.C. (GB) 1986-04-22 US claimed
EP-0064199-B1 NOVEL SECALONIC ACID DERIVATIVES AND METHOD FOR PREPARING THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-08-21 EP claimed