Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4EBP1 | Q13541 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29661849 | 0.95 | EIF4EBP1 (0.85) | EIF4EBP1 | |
| SCHEMBL22866768 | 0.95 | EIF4EBP1 (0.85) | EIF4EBP1 | |
| SCHEMBL29661915 | 0.93 | EIF4EBP1 (0.85) | EIF4EBP1 | |
| SCHEMBL29560096 | 0.93 | EIF4EBP1 (0.84) | EIF4EBP1 | |
| SCHEMBL22866523 | 0.93 | EIF4EBP1 (0.84) | EIF4EBP1 | |
| SCHEMBL29560206 | 0.93 | EIF4EBP1 (0.84) | EIF4EBP1 | |
| SCHEMBL22866774 | 0.92 | EIF4EBP1 (0.84) | EIF4EBP1 | |
| SCHEMBL28715277 | 0.92 | EIF4EBP1 (0.90) | EIF4EBP1 | |
| SCHEMBL22866702 | 0.91 | EIF4EBP1 (0.75) | EIF4EBP1 | |
| SCHEMBL29661940 | 0.91 | EIF4EBP1 (0.75) | EIF4EBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3994139-A1 | EIF4E-INHIBITING 4-OXO-3,4-DIHYDROPYRIDO[3,4-D]PYRIMIDINE COMPOUNDS | Effector Therapeutics Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| CN-114269756-A | 4-oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds inhibiting EIF4E | 效应疗法股份有限公司 | 2022-04-01 | — | — | CN | disclosed |