Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 10/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207168 | 1.00 | HCRTR1 (0.44) | HCRTR1HPGDLIPEGABRA5HSD11B1 | |
| SCHEMBL19256718 | 1.00 | HCRTR1 (0.44) | HCRTR1HPGDLIPEGABRA5HSD11B1 | |
| SCHEMBL19256719 | 1.00 | HCRTR1 (0.44) | HCRTR1HPGDLIPEGABRA5HSD11B1 | |
| SCHEMBL19256479 | 0.79 | HCRTR1 (0.45) | HCRTR1 | |
| SCHEMBL19256197 | 0.79 | HCRTR1 (0.45) | HCRTR1 | |
| SCHEMBL24381177 | 0.79 | HCRTR1 (0.45) | HCRTR1 | |
| SCHEMBL19256198 | 0.79 | HCRTR1 (0.45) | HCRTR1 | |
| Bromide SCHEMBL19207102 | 0.78 | HCRTR1 (0.45) | HCRTR1 | |
| Bromide SCHEMBL29560199 | 0.78 | HCRTR1 (0.45) | HCRTR1 | |
| SCHEMBL24381545 | 0.76 | HCRTR1 (0.59) | HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414241-B1 | HALO-SUBSTITUTED PIPERIDINES AS OREXIN RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2022-05-04 | — | — | EP | disclosed |