Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956081 | 1.00 | TDP1 (1.00) | TDP1ABCB1POLBMAPK1TSHR | |
| SCHEMBL13168216 | 0.98 | TDP1 (0.96) | TDP1ABCB1POLBMAPK1TSHR | |
| SCHEMBL826717 | 0.98 | TDP1 (0.96) | TDP1ABCB1POLBMAPK1TSHR | |
| SCHEMBL270042 | 0.98 | TDP1 (0.96) | TDP1ABCB1POLBMAPK1TSHR | |
| SCHEMBL7149374 | 0.98 | TDP1 (0.96) | TDP1ABCB1POLBMAPK1TSHR | |
| SCHEMBL7150717 | 0.98 | TDP1 (0.96) | TDP1ABCB1POLBMAPK1TSHR | |
| SCHEMBL2175855 | 0.98 | TDP1 (0.96) | TDP1ABCB1POLBMAPK1TSHR | |
| SCHEMBL7152317 | 0.98 | TDP1 (0.96) | TDP1ABCB1POLBMAPK1TSHR | |
| SCHEMBL7154355 | 0.93 | TDP1 (0.88) | TDP1ABCB1POLBMAPK1TSHR | |
| SCHEMBL7146329 | 0.93 | TDP1 (0.88) | TDP1ABCB1POLBMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747262-B1 | CONSERVED INNER CORE LIPOPOLYSACCHARIDE EPITOPES AS MULTI-SPECIES VACCINE CANDIDATES | CA NAT RESEARCH COUNCIL (CA) | 2012-09-26 | — | — | EP | disclosed |
| US-7759070-B2 | Conserved inner core lipopolysaccharide epitopes as multi-species vaccine candidates | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2010-07-20 | — | — | US | disclosed |
| EP-1747262-A4 | CONSERVED INNER CORE LIPOPOLYSACCHARIDE EPITOPES AS MULTI-SPECIES VACCINE CANDIDATES | CA NAT RESEARCH COUNCIL (CA) | 2009-02-11 | — | — | EP | disclosed |
| US-20080008723-A1 | comprising a conserved di-glucosyl -tri-heptosyl inner-core moiety ; Actinobacillus pleuropneumoniae (Ap), Mannheimia haemolytica (Mh) and Pasteurella multocida (Pm); toxoids | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2008-01-10 | — | — | US | disclosed |
| EP-1747262-A1 | CONSERVED INNER CORE LIPOPOLYSACCHARIDE EPITOPES AS MULTI-SPECIES VACCINE CANDIDATES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111196-A1 | CONSERVED INNER CORE LIPOPOLYSACCHARIDE EPITOPES AS MULTI-SPECIES VACCINE CANDIDATES | NATIONAL RESEARCH COUNCIL CANADA (CA) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080008723-A1 | comprising a conserved di-glucosyl -tri-heptosyl inner-core moiety ; Actinobacillus pleuropneumoniae (Ap), Mannheimia haemolytica (Mh) and Pasteurella multocida (Pm); toxoids | GMDS, MGAM, MLEC | TDP1 4284/4885ABCB1 4833/4885POLB 3891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.