SCHEMBL29562144

SCHEMBL29562144

N#Cc1cccc(-c2ccc3nc(C4CCCN4C#N)oc3c2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19385043 1.00 USP30 (1.00) USP30
SCHEMBL19385046 1.00 USP30 (1.00) USP30
SCHEMBL19385042 0.92 USP30 (1.00) USP30
SCHEMBL19385040 0.92 USP30 (1.00) USP30
SCHEMBL29562571 0.84 USP30 (1.00) USP30
SCHEMBL19384987 0.84 USP30 (1.00) USP30
SCHEMBL19384988 0.84 USP30 (1.00) USP30
SCHEMBL29562377 0.84 USP30 (1.00) USP30
SCHEMBL19385376 0.80 USP30 (0.80) USP30
SCHEMBL19385065 0.79 USP30 (1.00) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3433246-B1 1-CYANO-PYRROLIDINE DERIVATIVES AS DBU INHIBITORS MISSION THERAPEUTICS LTD (GB) 2022-05-04 — — EP disclosed
Send feedback