SCHEMBL29563407

SCHEMBL29563407

N#CN1CCCC1c1nnc(-c2cccc(-c3ccccc3)n2)[nH]1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29562896 0.87 USP30 (0.59) USP30
SCHEMBL29562286 0.82 USP30 (0.47) USP30
SCHEMBL29563528 0.81 USP30 (0.57) USP30
SCHEMBL29562199 0.81 USP30 (0.67) USP30
SCHEMBL19385004 0.81 USP30 (0.67) USP30
SCHEMBL19385347 0.77 USP30 (1.00) USP30
SCHEMBL29562305 0.77 USP30 (1.00) USP30
SCHEMBL29562247 0.77 USP30 (0.66) USP30
SCHEMBL29563356 0.76 USP30 (0.59) USP30
SCHEMBL19400823 0.73 USP30 (0.83) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3433246-B1 1-CYANO-PYRROLIDINE DERIVATIVES AS DBU INHIBITORS MISSION THERAPEUTICS LTD (GB) 2022-05-04 — — EP disclosed
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