Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4998500 | 0.77 | TDP1 (0.39) | TDP1SMN1; SMN2SLC22A6CACNA2D1ALDH1A1 | |
| SCHEMBL7518559 | 0.75 | SLC22A6 (0.39) | TDP1SMN1; SMN2MMESLC22A6CACNA2D1 | |
| SCHEMBL29974453 | 0.72 | TDP1 (0.39) | TDP1SMN1; SMN2SLC22A6ALDH1A1 | |
| SCHEMBL27431676 | 0.71 | TDP1 (0.37) | TDP1SMN1; SMN2SLC22A6ALDH1A1 | |
| SCHEMBL4998060 | 0.71 | SLC22A6 (0.31) | TDP1SLC22A6 | |
| SCHEMBL6435732 | 0.70 | TDP1 (0.40) | TDP1SMN1; SMN2MMESLC22A6CACNA2D1 | |
| SCHEMBL19729271 | 0.70 | TDP1 (0.40) | TDP1SMN1; SMN2MMESLC22A6CACNA2D1 | |
| SCHEMBL196267 | 0.69 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6CACNA2D1ALDH1A1 | |
| SCHEMBL6006627 | 0.69 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6CACNA2D1ALDH1A1 | |
| SCHEMBL196268 | 0.69 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6CACNA2D1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073502-A1 | USE OF BIOMARKER IN PREPARATION OF LUNG CANCER DETECTION REAGENT AND RELATED METHOD | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 2022-04-14 | — | — | WO | disclosed |