SCHEMBL29564288

SCHEMBL29564288

NCCCC[C@@H](NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](N)CS)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 5/20 0.63
▸ ENPEP Q07075 5/20 0.45
▸ RIMKLA Q8IXN7 1/20 0.44
▸ NAALAD2 Q9Y3Q0 1/20 0.44
▸ FNTA P49354 2/20 0.42
▸ FNTB P49356 2/20 0.42
▸ PGGT1B P53609 1/20 0.42
▸ BMP1 P13497 1/20 0.42
▸ ANPEP P15144 2/20 0.41
▸ GSR P00390 1/20 0.41
▸ GNPAT O15228 1/20 0.41
▸ CPB2 Q96IY4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368560 1.00 FOLH1 (0.63) FOLH1ENPEPRIMKLANAALAD2FNTA
SCHEMBL30234159 1.00 FOLH1 (0.63) FOLH1ENPEPRIMKLANAALAD2FNTA
SCHEMBL30811199 1.00 FOLH1 (0.63) FOLH1ENPEPRIMKLANAALAD2FNTA
SCHEMBL23857928 0.93 FOLH1 (0.51) FOLH1FNTAFNTBPGGT1BGSR
SCHEMBL29642982 0.93 FOLH1 (0.51) FOLH1FNTAFNTBPGGT1BGSR
SCHEMBL30307570 0.93 FOLH1 (0.51) FOLH1FNTAFNTBPGGT1BGSR
SCHEMBL30307583 0.93 FOLH1 (0.51) FOLH1FNTAFNTBPGGT1BGSR
SCHEMBL31520392 0.93 FOLH1 (0.51) FOLH1FNTAFNTBPGGT1BGSR
SCHEMBL30856932 0.93 FOLH1 (0.51) FOLH1FNTAFNTBPGGT1BGSR
SCHEMBL31679371 0.92 FOLH1 (0.50) FOLH1FNTAFNTBPGGT1BGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4171621-A1 C825 EXPRESSING IMMUNE CELLS AND DIAGNOSTIC USES THEREOF Memorial Sloan Kettering Cancer Center (US) 2023-05-03 — — EP claimed
EP-4419567-A2 ANTI-TSHR MULTI-SPECIFIC ANTIBODIES AND USES THEREOF Memorial Sloan Kettering Cancer Center (US) 2024-08-28 — — EP disclosed
EP-4171621-A1 C825 EXPRESSING IMMUNE CELLS AND DIAGNOSTIC USES THEREOF Memorial Sloan Kettering Cancer Center (US) 2023-05-03 — — EP disclosed
WO-2023069341-A2 ANTI-TSHR MULTI-SPECIFIC ANTIBODIES AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2023-04-27 — — WO disclosed
EP-4025609-A1 ANTI-STEAP1 ANTIBODIES AND USES THEREOF Memorial Sloan Kettering Cancer Center (US) 2022-07-13 — — EP disclosed
EP-3990022-A1 ANTI-CD33 ANTIBODIES FOR TREATING CANCER Memorial Sloan Kettering Cancer Center (US) 2022-05-04 — — EP disclosed
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