Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 10/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23675326 | 1.00 | HPGD (0.49) | HPGDIRAK4PTK2MGLL | |
| SCHEMBL23675155 | 0.91 | HPGD (0.46) | HPGDIRAK4MGLL | |
| SCHEMBL29564963 | 0.89 | HPGD (0.54) | HPGDPTK2MGLL | |
| SCHEMBL23675145 | 0.89 | HPGD (0.54) | HPGDPTK2MGLL | |
| SCHEMBL23675235 | 0.88 | HPGD (0.53) | HPGDPTK2MGLL | |
| SCHEMBL29673063 | 0.86 | HPGD (0.48) | HPGDPTK2MGLL | |
| SCHEMBL28887253 | 0.86 | HPGD (0.48) | HPGDPTK2MGLL | |
| SCHEMBL29565007 | 0.82 | HPGD (0.57) | HPGDPTK2MGLL | |
| SCHEMBL23675325 | 0.82 | HPGD (0.57) | HPGDPTK2MGLL | |
| SCHEMBL24942913 | 0.81 | HPGD (0.61) | HPGDMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335043-B | PGDH inhibitors and methods of making and using the same | 迈欧伏特治疗公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-117377668-A | Inhalant formulations of PGDH inhibitors and methods of use thereof | 迈欧伏特治疗公司 | 2024-01-09 | — | — | CN | disclosed |
| EP-4228650-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | Epirium Bio Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| EP-4093385-A1 | PGDH INHIBITORS AND METHODS OF MAKING AND USING | Myoforte Therapeutics Inc. (US) | 2022-11-30 | — | — | EP | disclosed |
| CN-115335043-A | PGDH inhibitors and methods of making and using | 迈欧伏特治疗公司 | 2022-11-11 | — | — | CN | disclosed |
| WO-2022082009-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | EPIRIUM BIO INC. (US) | 2022-04-21 | — | — | WO | disclosed |