SCHEMBL29566239

SCHEMBL29566239

Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCNC(=O)COc1cccc3c1C(=O)N(C1CCC(=O)NC1=O)C3=O)c1nnc(C)n1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 1.00
DDB1 Q16531 19/20 1.00
BRD4 O60885 15/20 1.00
BRD3 Q15059 1/20 1.00
BRDT Q58F21 1/20 1.00
TRIM24 O15164 1/20 0.99
TRIM33 Q9UPN9 1/20 0.99
BET1 O15155 1/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30146573 1.00 CRBN (1.00) CRBNDDB1BRD4BRD3BRDT
SCHEMBL19556879 1.00 CRBN (1.00) CRBNDDB1BRD4BRD3BRDT
SCHEMBL19556893 1.00 CRBN (1.00) CRBNDDB1BRD4BRD3BRDT
SCHEMBL17859034 1.00 CRBN (1.00) CRBNDDB1BRD4BRD3BRDT
SCHEMBL19556887 1.00 CRBN (1.00) CRBNDDB1BRD4BRD3BRDT
SCHEMBL19556839 1.00 CRBN (1.00) CRBNDDB1BRD4BRD3BRDT
SCHEMBL17553399 1.00 CRBN (1.00) CRBNDDB1BRD4BRD3BRDT
SCHEMBL19556892 1.00 CRBN (1.00) CRBNDDB1BRD4BRD3BRDT
SCHEMBL23789740 0.99 CRBN (1.00) CRBNDDB1BRD4BRD3BRDT
SCHEMBL17859001 0.99 CRBN (1.00) CRBNDDB1BRD4BRD3BRDT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240245664-A1 METHODS OF USING USP15 INHIBITORS THE CURATORS OF THE UNIVERSITY OF MISSOURI 2024-07-25 US disclosed
US-20220111044-A1 WHOLE CELL TUMOR VACCINES AND METHODS OF USE THEROF CHILDREN'S NATIONAL MEDICAL CENTER 2022-04-14 US disclosed