Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 11/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.81 |
| ▸ | CD74 | P04233 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2757836 | 1.00 | MIF (1.00) | MIFKMT2AMEN1POLBCD74 | |
| SCHEMBL2757837 | 0.90 | MIF (1.00) | MIFKMT2AMEN1POLBCD74 | |
| SCHEMBL18805704 | 0.89 | MIF (0.81) | MIFKMT2AMEN1POLBCD74 | |
| SCHEMBL18805703 | 0.86 | MIF (1.00) | MIFKMT2AMEN1POLBCD74 | |
| SCHEMBL18805676 | 0.85 | KMT2A (0.76) | MIFKMT2AMEN1POLBCD74 | |
| SCHEMBL10874258 | 0.85 | MIF (1.00) | MIFKMT2AMEN1POLBCD74 | |
| SCHEMBL13086455 | 0.85 | MIF (1.00) | MIFKMT2AMEN1POLBCD74 | |
| SCHEMBL2757838 | 0.85 | IDO1 (0.81) | MIFKMT2AMEN1POLBCD74 | |
| SCHEMBL13086565 | 0.85 | KMT2A (0.81) | MIFKMT2AMEN1POLBCD74 | |
| SCHEMBL18805692 | 0.85 | IDO1 (0.81) | MIFKMT2AMEN1POLBCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237002-A1 | METHODS OF TREATING SPONDYLOARTHRITIS OR SYMPTOMS THEREOF | University Health Network (CA) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022087719-A1 | METHODS OF TREATING SPONDYLOARTHRITIS OR SYMPTOMS THEREOF | UNIVERSITY HEALTH NETWORK (CA) | 2022-05-05 | — | — | WO | disclosed |