Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 10/20 | 0.63 |
| ▸ | CA2 | P00918 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29565511 | 0.90 | CA9 (0.61) | CA9CA2MAPTKMT2AMEN1 | |
| SCHEMBL29565287 | 0.89 | CA9 (0.67) | CA9CA2MAPTKMT2AMEN1 | |
| SCHEMBL29565517 | 0.89 | CA9 (0.59) | CA9CA2MAPTKMT2AMEN1 | |
| SCHEMBL29565128 | 0.87 | CA9 (0.64) | CA9CA2MAPTKMT2AMEN1 | |
| SCHEMBL29565431 | 0.87 | CA9 (0.67) | CA9CA2MAPTKMT2AMEN1 | |
| SCHEMBL29565477 | 0.86 | CA9 (0.66) | CA9CA2MAPTKMT2AMEN1 | |
| SCHEMBL29566117 | 0.85 | CA9 (0.84) | CA9CA2MAPTKMT2AMEN1 | |
| SCHEMBL29565426 | 0.85 | CA9 (0.62) | CA9CA2MAPTKMT2AMEN1 | |
| SCHEMBL29565696 | 0.85 | CA9 (0.62) | CA9CA2MAPTKMT2AMEN1 | |
| SCHEMBL29565100 | 0.83 | CA9 (0.84) | CA9CA2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022075805-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER | 연세대학교 산학협력단 | 2022-04-14 | — | — | WO | claimed |
| WO-2022075805-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER | 연세대학교 산학협력단 | 2022-04-14 | — | — | WO | disclosed |