Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21910356 | 1.00 | RET (0.56) | RET | |
| SCHEMBL22660720 | 0.88 | RET (0.56) | RET | |
| SCHEMBL21910360 | 0.81 | RET (0.51) | RET | |
| SCHEMBL29566512 | 0.81 | RET (0.51) | RET | |
| SCHEMBL29483174 | 0.81 | RET (0.53) | RET | |
| SCHEMBL20070844 | 0.81 | RET (0.53) | RET | |
| SCHEMBL20154601 | 0.80 | RET (0.50) | RET | |
| SCHEMBL25263188 | 0.79 | RET (0.46) | RET | |
| SCHEMBL22660585 | 0.78 | RET (0.54) | RET | |
| SCHEMBL29483020 | 0.78 | RET (0.54) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380825-B | Substituted pyrazole condensed ring derivative and preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-112771043-B | Substituted pyrazole condensed ring derivative and preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-114380825-A | Substituted pyrazole fused ring derivative and preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2022-04-22 | — | — | CN | disclosed |