Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 10/20 | 1.00 |
| ▸ | CD74 | P04233 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | TNIK | Q9UKE5 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CBX7 | O95931 | 1/20 | 0.56 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.56 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.56 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805682 | 1.00 | MIF (1.00) | MIFCD74POLBTNIKMEN1 | |
| SCHEMBL3270711 | 0.91 | MIF (1.00) | MIFCD74POLBTNIKMEN1 | |
| SCHEMBL29566319 | 0.90 | MIF (0.84) | MIFCD74POLBTNIKMEN1 | |
| SCHEMBL244817 | 0.90 | MIF (0.84) | MIFCD74POLBTNIKMEN1 | |
| SCHEMBL242399 | 0.87 | MIF (0.77) | MIFCD74POLBTNIKMEN1 | |
| SCHEMBL2757851 | 0.87 | MIF (1.00) | MIFCD74POLBTNIKMEN1 | |
| SCHEMBL18805704 | 0.86 | MIF (0.81) | MIFCD74POLBMEN1KMT2A | |
| SCHEMBL29566444 | 0.86 | MIF (0.77) | MIFCD74POLBTNIKMEN1 | |
| SCHEMBL18805688 | 0.86 | MIF (0.77) | MIFCD74POLBTNIKMEN1 | |
| SCHEMBL29567415 | 0.86 | MIF (0.77) | MIFCD74POLBTNIKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237002-A1 | METHODS OF TREATING SPONDYLOARTHRITIS OR SYMPTOMS THEREOF | University Health Network (CA) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022087719-A1 | METHODS OF TREATING SPONDYLOARTHRITIS OR SYMPTOMS THEREOF | UNIVERSITY HEALTH NETWORK (CA) | 2022-05-05 | — | — | WO | disclosed |