⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61229 | 0.77 | — | — | |
| SCHEMBL423990 | 0.75 | — | — | |
| SCHEMBL232489 | 0.75 | — | — | |
| SCHEMBL195702 | 0.75 | — | — | |
| SCHEMBL11584320 | 0.75 | — | — | |
| SCHEMBL1029285 | 0.75 | — | — | |
| SCHEMBL443906 | 0.75 | — | — | |
| SCHEMBL75807 | 0.75 | — | — | |
| SCHEMBL1031265 | 0.75 | — | — | |
| SCHEMBL3395205 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102440-A | Preparation method of 1- (3, 4-diaminophenyl) ethanone | 上海琼燕医药科技有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-110498923-B | Ultrahigh-temperature-resistant easy-to-mold polyimide resin and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-03-28 | — | — | CN | claimed |
| CN-115710231-A | Asymmetric thioether impurity C 30 H 21 N 5 O 4 Preparation method of S | 陕西汉江药业集团股份有限公司 | 2023-02-24 | — | — | CN | claimed |
| CN-113214342-A | 23-hydroxy betulinic acid 3-site modified derivative, preparation method and application | 中国药科大学 | 2021-08-06 | — | — | CN | claimed |
| CN-107501380-A | 23 hydroxyl radical white birck acid 23 modified derivative, preparation method and the usages | 中国药科大学 | 2017-12-22 | — | — | CN | claimed |
| CN-104086452-B | A kind of shortening prepares the method for high purity (3,4-diamino-phenyl) (4-fluorophenyl) ketone | Changzhou Qi Hui pharmaceutcal corporation, Ltd (CN) | 2016-04-06 | — | — | CN | claimed |
| US-8975259-B2 | Compositions and methods for inhibiting G protein signaling | UNIVERSITY OF ROCHESTER (US) | 2015-03-10 | — | — | US | claimed |
| CN-104086452-A | Method for preparing high-purity (3,4-diaminophenyl)(4-fluorophenyl) ketone by virtue of catalytic hydrogenation | CHANGZHOU YABANG QH PHARMACHEM CO LTD | 2014-10-08 | — | — | CN | claimed |
| US-20100130505-A1 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIVERSITY OF ROCHESTER (US) | 2010-05-27 | — | — | US | claimed |
| EP-2147310-A2 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | University of Rochester (US) | 2010-01-27 | — | — | EP | claimed |
| WO-2005009968-A1 | QUINOLINE DERIVATES AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2005-02-03 | — | — | WO | claimed |
| EP-1289950-B1 | SERINE PROTEASE INHIBITORS | LILLY CO ELI (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1289972-B1 | SERINE PROTEASE INHIBITORS | LILLY CO ELI (US) | 2004-09-08 | — | — | EP | claimed |
| EP-0928291-B1 | 3-MERCAPTOACETYLAMINO-1,5-SUBSTITUTED-2-OXO-AZEPAN DERIVATIVES USEFUL AS INHIBITORS OF MATRIX METALLOPROTEINASE | AVENTIS PHARMA INC (US) | 2002-12-04 | — | — | EP | claimed |
| EP-0928291-A1 | 3-MERCAPTOACETYLAMINO-1,5-SUBSTITUTED-2-OXO-AZEPAN DERIVATIVES USEFUL AS INHIBITORS OF MATRIX METALLOPROTEINASE | HOECHST MARION ROUSSEL, INC. (US) | 1999-07-14 | — | — | EP | claimed |
| WO-1998012211-A1 | 3-MERCAPTOACETYLAMINO-1,5-SUBSTITUTED-2-OXO-AZEPAN DERIVATIVES USEFUL AS INHIBITORS OF MATRIX METALLOPROTEINASE | HOECHST MARION ROUSSEL, INC. (US) | 1998-03-26 | — | — | WO | claimed |
| US-5288816-A | High glass transition temperature; stability | THE DOW CHEMICAL COMPANY (US) | 1994-02-22 | — | — | US | claimed |
| WO-1994003557-A1 | NOVEL NONLINEAR OPTICAL AMINOARYL HYDRAZONES AND NONLINEAR OPTICAL POLYMERS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1994-02-17 | — | — | WO | claimed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |