SCHEMBL29569815

SCHEMBL29569815

NC(=O)NCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.55
MDM2 Q00987 6/20 0.54
MDM4 O15151 1/20 0.52
TP53 P04637 1/20 0.52
TLR2 O60603 2/20 0.52
C3AR1 Q16581 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31647336 1.00 KMT2A (0.55) KMT2AMDM2MDM4TP53TLR2
SCHEMBL119468 1.00 KMT2A (0.55) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29362229 1.00 KMT2A (0.55) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29850382 1.00 KMT2A (0.55) KMT2AMDM2MDM4TP53TLR2
SCHEMBL13401519 1.00 KMT2A (0.55) KMT2AMDM2MDM4TP53TLR2
SCHEMBL25356641 1.00 KMT2A (0.55) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29401148 1.00 KMT2A (0.55) KMT2AMDM2MDM4TP53TLR2
SCHEMBL4600663 0.97 KMT2A (0.56) KMT2AMDM2MDM4TP53TLR2
SCHEMBL4882849 0.97 KMT2A (0.56) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29401108 0.97 KMT2A (0.56) KMT2AMDM2MDM4TP53TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4637833-A2 CEREBLON DEGRADER CONJUGATES, AND USES THEREOF Genentech, Inc. (US) 2025-10-29 EP disclosed
WO-2024138128-A2 CEREBLON DEGRADER CONJUGATES, AND USES THEREOF GENENTECH, INC. (US) 2024-06-27 WO disclosed
EP-4237008-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF Elucida Oncology, Inc. (US) 2023-09-06 EP disclosed
CN-113185693-B Polyamide acid solution and preparation method thereof, polyimide and polyimide film 吉林奥来德光电材料股份有限公司 2022-05-06 CN disclosed
WO-2022093800-A2 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. (US) 2022-05-05 WO disclosed