Benzofuran

Benzofuran

SCHEMBL2957261

CC(=O)c1cc2ccccc2o1.c1ccc2occc2c1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 1/20 0.57
NPC1 O15118 7/20 0.51
RAB9A P51151 7/20 0.51
SMN1; SMN2 Q16637 5/20 0.51
ALDH1A1 P00352 4/20 0.51
HPGD P15428 4/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
KDM4E B2RXH2 2/20 0.51
LMNA P02545 2/20 0.51
MAPK1 P28482 2/20 0.51
HSD17B10 Q99714 2/20 0.51
GLA P06280 1/20 0.51
GAA P10253 1/20 0.51
CASP1 P29466 1/20 0.51
BRCA1 P38398 1/20 0.51
CASP7 P55210 1/20 0.51
TSHR P16473 1/20 0.51
MAPT P10636 5/20 0.50
CA12 O43570 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241548 0.88 FLT3 (0.71) FLT3NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL27690690 0.82 FLT3 (0.62) FLT3NPC1RAB9ASMN1; SMN2ALDH1A1
Benzofuran SCHEMBL28034570 0.81 CTNNB1 (0.42) FLT3NPC1RAB9ASMN1; SMN2ALDH1A1
Benzofuran SCHEMBL28870582 0.81 CTNNB1 (0.45) FLT3SMN1; SMN2ALDH1A1HPGDMEN1
Benzofuran SCHEMBL7029052 0.79 CTNNB1 (0.47) FLT3NPC1RAB9ASMN1; SMN2ALDH1A1
Benzofuran SCHEMBL31275524 0.79 CTNNB1 (0.47) FLT3NPC1RAB9ASMN1; SMN2ALDH1A1
Benzofuran SCHEMBL11368578 0.79 CTNNB1 (0.47) FLT3NPC1RAB9ASMN1; SMN2ALDH1A1
Trifluoroacetic Acid SCHEMBL28751252 0.78 FLT3 (0.57) FLT3NPC1RAB9ASMN1; SMN2ALDH1A1
Benzofuran SCHEMBL1073865 0.78 CTNNB1 (0.46) FLT3NPC1RAB9ASMN1; SMN2ALDH1A1
Benzofuran SCHEMBL3898681 0.77 CTNNB1 (0.45) FLT3NPC1RAB9AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7846886-B2 Mixtures of unsaturated macrocyclic epoxides as odoriferous substances SYMRISE GMBH & CO. KG (DE) 2010-12-07 US disclosed
US-20090305928-A1 Mixtures of Unsaturated Macrocyclic Epoxides as Odoriferous Substances SYMRISE GMBH & CO. KG (DE) 2009-12-10 US disclosed
WO-2007090704-A1 MIXTURES OF UNSATURATED MACROCYCLIC EPOXIDES AS ODORIFEROUS SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2007-08-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090305928-A1 Mixtures of Unsaturated Macrocyclic Epoxides as Odoriferous Substances OXER1, OR10J3, OR51E2 FLT3 3770/4885NPC1 1932/4885RAB9A 4451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.