Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937891 | 1.00 | NPC1 (0.48) | NPC1NPSR1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL29573077 | 0.89 | NPC1 (0.43) | NPC1LMNASMN1; SMN2ELANEALDH1A1 | |
| SCHEMBL19792455 | 0.83 | POLB (0.49) | NPC1NPSR1LMNASMN1; SMN2ELANE | |
| SCHEMBL18544462 | 0.80 | SMN1; SMN2 (0.50) | NPC1NPSR1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL19497770 | 0.80 | MEN1 (0.50) | NPC1NPSR1S1PR2LMNASMN1; SMN2 | |
| SCHEMBL28937884 | 0.79 | SMN1; SMN2 (0.61) | NPC1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL22040024 | 0.77 | NPC1 (0.60) | NPC1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL22039979 | 0.77 | NPC1 (0.60) | NPC1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL19497780 | 0.77 | NPC1 (0.60) | NPC1LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL17570161 | 0.77 | NPC1 (0.60) | NPC1LMNASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777574-B | Synthesis method of N-alkyl naphtho [2,1-d ] thiazole-2-amine promoted by visible light | 湖南科技学院 | 2022-05-10 | — | — | CN | disclosed |