SCHEMBL29575208

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	6/20	0.74

▸	HCRTR1	O43613	1/20	0.64

▸	HCRTR2	O43614	1/20	0.64

▸	F2	P00734	4/20	0.64

▸	CRHR1	P34998	1/20	0.62

▸	CRHR2	Q13324	1/20	0.62

▸	NPY1R	P25929	2/20	0.61

▸	NPY2R	P49146	2/20	0.61

▸	NPY4R	P50391	2/20	0.61

▸	NPY5R	Q15761	2/20	0.61

▸	MAPK8	P45983	1/20	0.60

▸	MAPK9	P45984	1/20	0.60

▸	MAPK10	P53779	1/20	0.60

▸	APLNR	P35414	1/20	0.60

▸	GLP1R	P43220	1/20	0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30436605	0.91	CALCR (0.69)	CALCRHCRTR1HCRTR2CRHR1CRHR2
SCHEMBL29771870	0.90	CALCR (0.68)	CALCRF2CRHR1CRHR2NPY1R
SCHEMBL29771868	0.90	CALCR (0.68)	CALCRF2CRHR1CRHR2NPY1R
SCHEMBL29771869	0.90	CALCR (0.68)	CALCRF2CRHR1CRHR2NPY1R
SCHEMBL31182727	0.90	KDM1A (0.65)	CALCRHCRTR1HCRTR2F2NPY1R
SCHEMBL31464902	0.90	CALCR (0.69)	CALCRCRHR1CRHR2GLP1R
SCHEMBL31464899	0.90	CALCR (0.69)	CALCRCRHR1CRHR2GLP1R
SCHEMBL30466120	0.90	CALCR (0.70)	CALCRMAPK8MAPK9MAPK10APLNR
SCHEMBL31182872	0.90	CALCR (0.73)	CALCRHCRTR1HCRTR2F2CRHR1
SCHEMBL31504149	0.89	CALCR (0.67)	CALCRCRHR1CRHR2APLNRGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114456254-B	Synthesis method of C-type natriuretic peptide analogue Vosoritide	江苏诺泰澳赛诺生物制药股份有限公司	2023-06-16	—	—	CN	disclosed
CN-114456254-A	Synthesis method of C-type natriuretic peptide analogue Vosolitide	江苏诺泰澳赛诺生物制药股份有限公司	2022-05-10	—	—	CN	disclosed