⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714417 | 0.74 | — | — | |
| SCHEMBL172058 | 0.74 | — | — | |
| SCHEMBL6714410 | 0.74 | — | — | |
| Vinyl Chloride SCHEMBL27740258 | 0.70 | — | — | |
| SCHEMBL7636359 | 0.70 | — | — | |
| SCHEMBL11334518 | 0.70 | — | — | |
| SCHEMBL1407387 | 0.70 | — | — | |
| SCHEMBL8052611 | 0.70 | — | — | |
| SCHEMBL12226 | 0.70 | — | — | |
| SCHEMBL1407388 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1017430-B | Process for the preparation of 7 beta- [2- (2-amino-4-thiazolyl) alkenamido ] -3-cephem-4-carboxylic acid esters | SHIONOGI & CO (JP) | 1992-07-15 | — | — | CN | claimed |
| US-10894239-B2 | Dispersant, dispersion composition, and fibrous sheet | MEISEI CHEMICAL WORKS, LTD. (JP) | 2021-01-19 | — | — | US | disclosed |
| EP-3135369-B1 | USE OF DISPERSANT,DISPERSION COMPOSITION AND FIBROUS SHEET | MEISEI CHEMICAL WORKS LTD (JP) | 2020-08-19 | — | — | EP | disclosed |
| US-20170080397-A1 | DISPERSANT, DISPERSION COMPOSITION, AND FIBROUS SHEET | MEISEI CHEMICAL WORKS, LTD. (JP) | 2017-03-23 | — | — | US | disclosed |
| EP-3135369-A1 | DISPERSANT, DISPERSION COMPOSITION, AND FIBROUS SHEET | MEISEI CHEMICAL WORKS, LTD. (JP) | 2017-03-01 | — | — | EP | disclosed |
| CN-103987711-B | 8-carbamoyl-2- (2, 3-disubstituted pyridin-6-yl) -1,2,3, 4-tetrahydroisoquinoline derivatives as apoptosis inducers for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-102307872-B | BCL-2-selectively apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE 公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-103153993-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC. (BS) | 2016-06-01 | — | — | CN | disclosed |
| CN-103402521-B | Methods of treatment using selective BCL-2 inhibitors | ABBVIE INC. (BS) | 2016-01-20 | — | — | CN | disclosed |
| CN-105218483-A | Be used for the treatment of the cell death inducer of cancer and immunity and autoimmune disorder | ABBVIE INC | 2016-01-06 | — | — | CN | disclosed |
| EP-0888271-A4 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | BERLEX LAB (US) | 2000-03-15 | — | — | EP | disclosed |
| US-5994375-A | ANTICOAGULANTS | BERLEX LABORATORIES, INC. (US) | 1999-11-30 | — | — | US | disclosed |
| CN-1211232-A | Benzamidine derivatives substituted with amino acid and hydroxy acid derivatives and their use as anticoagulants | BERLEX LAB (US) | 1999-03-17 | — | — | CN | disclosed |
| EP-0888271-A1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997029067-A1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (DE) | 1997-08-14 | — | — | WO | disclosed |
| US-5260444-A | Cardiovascular, hypotensive | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-11-09 | — | — | US | disclosed |
| US-5208245-A | Hypotensive agents | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-05-04 | — | — | US | disclosed |
| EP-0460418-A2 | Novel Dihydropyridine derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4332614-A | HALOACETANILIDE ETHERS | MONSANTO COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
| US-4183928-A | Haloarylmalonamidooxacephalosporins | SHIONOGI AND CO., LTD. (JP) | 1980-01-15 | — | — | US | disclosed |