SCHEMBL29575604

SCHEMBL29575604

C[C@H]1CN(Cc2cc(C(=O)Nc3cccc(C4(Cc5nncn5C)COC4)c3)nc(C3CC3)c2)CCC1(F)F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 1.00
▸ CBLC Q9ULV8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22528146 1.00 CBLB (1.00) CBLBCBLC
SCHEMBL22528101 1.00 CBLB (1.00) CBLBCBLC
SCHEMBL29575250 1.00 CBLB (1.00) CBLBCBLC
SCHEMBL21200263 0.91 CBLB (0.83) CBLBCBLC
SCHEMBL29867060 0.91 CBLB (0.83) CBLBCBLC
SCHEMBL24750095 0.91 CBLB (0.83) CBLBCBLC
SCHEMBL21212485 0.90 CBLB (0.81) CBLBCBLC
SCHEMBL29866800 0.90 CBLB (0.81) CBLBCBLC
SCHEMBL21200214 0.89 CBLB (0.79) CBLBCBLC
SCHEMBL21200878 0.88 CBLB (0.78) CBLBCBLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114364667-B 3-Substituted piperidines for Cbl-b inhibition and use of Cbl-b inhibitors in combination with cancer vaccines and/or oncolytic viruses 紐力克斯治疗公司 2025-01-10 — — CN disclosed
CN-114364667-A 3-substituted piperidines for Cbl-b inhibition and the use of Cbl-b inhibitors in combination with cancer vaccines and/or oncolytic viruses 紐力克斯治疗公司 2022-04-15 — — CN disclosed
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