Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 19/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17919722 | 1.00 | KDM2B (1.00) | KDM2BMEN1ALDH1A1KMT2A | |
| SCHEMBL21926832 | 0.84 | KDM2B (0.73) | KDM2BMEN1ALDH1A1KMT2A | |
| SCHEMBL17913852 | 0.84 | KDM2B (1.00) | KDM2BMEN1ALDH1A1KMT2A | |
| SCHEMBL29577176 | 0.84 | KDM2B (1.00) | KDM2BMEN1ALDH1A1KMT2A | |
| SCHEMBL17919631 | 0.83 | KDM2B (0.72) | KDM2B | |
| SCHEMBL17919752 | 0.83 | KDM2B (1.00) | KDM2BMEN1ALDH1A1KMT2A | |
| SCHEMBL19798980 | 0.83 | KDM2B (1.00) | KDM2BMEN1ALDH1A1KMT2A | |
| SCHEMBL21120889 | 0.83 | KDM2B (0.71) | KDM2BMEN1ALDH1A1KMT2A | |
| SCHEMBL29576567 | 0.83 | KDM2B (1.00) | KDM2BMEN1ALDH1A1KMT2A | |
| SCHEMBL17913755 | 0.80 | KDM2B (1.00) | KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406414-B | (piperidin-3-yl) (naphthalen-2-yl) methanone derivatives as inhibitors of histone demethylase KDM2B for the treatment of cancer | 基因泰克公司 | 2022-04-19 | — | — | CN | disclosed |