Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5042203 | 0.95 | MAOB (0.34) | GAAMAOBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5042200 | 0.95 | MAOB (0.34) | GAAMAOBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29577679 | 0.95 | MAOB (0.39) | GAAMAOBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13749945 | 0.90 | MAOB (0.36) | GAAMAOBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3489331 | 0.90 | MAOB (0.36) | GAAMAOBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3489329 | 0.90 | MAOB (0.36) | GAAMAOBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4299787 | 0.89 | MAOB (0.36) | GAAMAOBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4299790 | 0.89 | MAOB (0.36) | GAAMAOBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL482255 | 0.86 | GAA (0.37) | GAAMAOBMAPTALDH1A1 | |
| SCHEMBL29986851 | 0.86 | GAA (0.37) | GAAMAOBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069913-B | Bis (morpholinylalkoxy) quinazoline derivative and application thereof in anti-tumor aspect | 陕西师范大学 | 2022-03-01 | — | — | CN | disclosed |