Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 20/20 | 0.77 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22943210 | 1.00 | CHEK1 (0.77) | CHEK1CHEK2KCNH2 | |
| SCHEMBL26976841 | 0.88 | CHEK1 (0.67) | CHEK1CHEK2KCNH2 | |
| SCHEMBL22944497 | 0.88 | CHEK1 (0.77) | CHEK1CHEK2 | |
| SCHEMBL22944460 | 0.88 | CHEK1 (0.66) | CHEK1CHEK2KCNH2 | |
| SCHEMBL29578234 | 0.88 | CHEK1 (0.66) | CHEK1CHEK2KCNH2 | |
| SCHEMBL620093 | 0.87 | CHEK1 (1.00) | CHEK1CHEK2 | |
| SCHEMBL26976896 | 0.87 | CHEK1 (0.78) | CHEK1CHEK2 | |
| SCHEMBL22944622 | 0.86 | CHEK1 (0.58) | CHEK1CHEK2 | |
| SCHEMBL26976925 | 0.86 | CHEK1 (0.66) | CHEK1CHEK2 | |
| SCHEMBL22944179 | 0.84 | CHEK1 (0.61) | CHEK1CHEK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4298095-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | Sperogenix Therapeutics Limited (HK) | 2024-01-03 | — | — | EP | claimed |
| WO-2022162606-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | SPEROGENIX THERAPEUTICS LIMITED (CN) | 2022-08-04 | — | — | WO | claimed |
| CN-114728949-B | Heterocyclic compounds as kinase inhibitors and uses thereof | 曙方医药 | 2024-11-12 | — | — | CN | disclosed |
| EP-4298095-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | Sperogenix Therapeutics Limited (HK) | 2024-01-03 | — | — | EP | disclosed |
| WO-2022162606-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | SPEROGENIX THERAPEUTICS LIMITED (CN) | 2022-08-04 | — | — | WO | disclosed |
| EP-4007757-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | Integral Biosciences Pvt. Ltd. (IN) | 2022-06-08 | — | — | EP | disclosed |