Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 5/20 | 0.59 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580071 | 0.92 | CALCRL (0.61) | CALCRLRAMP1SLC6A2CMA1OPRD1 | |
| SCHEMBL29579489 | 0.92 | CALCRL (0.64) | CALCRLRAMP1SLC6A2CMA1OPRD1 | |
| SCHEMBL29579716 | 0.92 | CALCRL (0.61) | CALCRLRAMP1SLC6A2CMA1OPRD1 | |
| SCHEMBL29579706 | 0.91 | CALCRL (0.60) | CALCRLRAMP1F2SLC6A2CMA1 | |
| SCHEMBL29579417 | 0.90 | CALCRL (0.62) | CALCRLRAMP1SLC6A2CMA1 | |
| SCHEMBL29579122 | 0.90 | CALCRL (0.59) | CALCRLRAMP1SLC6A2CMA1 | |
| SCHEMBL29580098 | 0.90 | SLC6A2 (0.64) | CALCRLRAMP1SLC6A2OPRD1OPRM1 | |
| SCHEMBL30603858 | 0.89 | CALCRL (0.53) | CALCRLRAMP1F2NTSR2NTSR1 | |
| SCHEMBL31694408 | 0.88 | F2 (0.58) | CALCRLRAMP1F2SLC6A2ACE | |
| SCHEMBL29579934 | 0.87 | CALCRL (0.57) | CALCRLRAMP1SLC6A2CMA1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | AUBURN UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | NATIONAL SCIENCE FOUNDATION | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | VIP, PTMS, IAPP | CALCRL 78/4885RAMP1 1411/4885F2 451/4885 |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | VIP, PTMS, IAPP | CALCRL 78/4885RAMP1 1411/4885F2 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.