Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.59 |
| ▸ | BTK | Q06187 | 3/20 | 0.49 |
| ▸ | AR | P10275 | 5/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.48 |
| ▸ | ITK | Q08881 | 2/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29579610 | 0.95 | CRBN (0.61) | CRBNBTKARIRAK1IRAK4 | |
| SCHEMBL29579304 | 0.95 | CRBN (0.61) | CRBNBTKARIRAK1IRAK4 | |
| SCHEMBL29132157 | 0.93 | CRBN (0.63) | CRBNBTKARIRAK1IRAK4 | |
| SCHEMBL27028395 | 0.93 | CRBN (0.63) | CRBNBTKARIRAK1IRAK4 | |
| SCHEMBL29132165 | 0.93 | CRBN (0.62) | CRBNBTKARIRAK1IRAK4 | |
| SCHEMBL22291629 | 0.89 | CRBN (0.57) | CRBNBTKARITKDDB1 | |
| SCHEMBL24480418 | 0.89 | CRBN (0.53) | CRBNBTKARIRAK1IRAK4 | |
| SCHEMBL29578832 | 0.89 | CRBN (0.53) | CRBNBTKARIRAK1IRAK4 | |
| SCHEMBL27176462 | 0.88 | CRBN (0.65) | CRBNBTKARIRAK1IRAK4 | |
| SCHEMBL29976419 | 0.87 | CRBN (0.57) | CRBNBTKARIRAK1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111526-A1 | BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | disclosed |