Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 10/20 | 1.00 |
| ▸ | F10 | P00742 | 10/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20584342 | 1.00 | KLKB1 (1.00) | KLKB1F10KCNH2 | |
| SCHEMBL24012263 | 0.89 | KLKB1 (0.81) | KLKB1F10KCNH2 | |
| SCHEMBL31456861 | 0.87 | KLKB1 (0.77) | KLKB1F10KCNH2 | |
| SCHEMBL28938012 | 0.86 | KLKB1 (0.76) | KLKB1F10 | |
| SCHEMBL20584258 | 0.85 | KLKB1 (0.74) | KLKB1F10KCNH2 | |
| SCHEMBL24570274 | 0.85 | KLKB1 (0.74) | KLKB1F10KCNH2 | |
| SCHEMBL29580848 | 0.85 | KLKB1 (0.74) | KLKB1F10KCNH2 | |
| SCHEMBL21726679 | 0.84 | KLKB1 (0.73) | KLKB1F10 | |
| SCHEMBL20446513 | 0.84 | KLKB1 (0.72) | KLKB1F10 | |
| SCHEMBL20446556 | 0.84 | KLKB1 (0.72) | KLKB1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591212-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-114591212-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-108289893-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-04-12 | — | — | CN | disclosed |