Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340557 | 0.87 | MEN1 (0.61) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL24341455 | 0.86 | DYRK3 (0.57) | MEN1RGS12USP2POLBMAPT | |
| Trifluoroacetic Acid SCHEMBL29583374 | 0.83 | ATM (0.47) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL7524308 | 0.82 | KMT2A (0.69) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL29583729 | 0.80 | MEN1 (0.51) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL24340556 | 0.79 | MEN1 (0.59) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL24340716 | 0.78 | HTT (0.49) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL24340736 | 0.76 | MEN1 (0.62) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL24340735 | 0.75 | MEN1 (0.57) | MEN1RGS12USP2POLBMAPT | |
| SCHEMBL24340555 | 0.71 | MEN1 (0.54) | MEN1RGS12USP2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022077052-A1 | PROBE COMPOUNDS FOR MITOCHONDIAL MEMBRANE IMAGING | THE UNIVERSITY OF SYDNEY (AU) | 2022-04-21 | — | — | WO | disclosed |