Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.33 |
| ▸ | CDK9 | P50750 | 4/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24423491 | 1.00 | FFAR4 (0.40) | FFAR4FFAR1TBK1TLR9TLR8 | |
| SCHEMBL29584553 | 1.00 | FFAR4 (0.40) | FFAR4FFAR1TBK1TLR9TLR8 | |
| SCHEMBL24423493 | 1.00 | FFAR4 (0.40) | FFAR4FFAR1TBK1TLR9TLR8 | |
| SCHEMBL29584811 | 1.00 | FFAR4 (0.40) | FFAR4FFAR1TBK1TLR9TLR8 | |
| SCHEMBL24424096 | 1.00 | FFAR4 (0.40) | FFAR4FFAR1TBK1TLR9TLR8 | |
| SCHEMBL24424523 | 0.92 | FFAR4 (0.37) | FFAR4FFAR1TBK1TLR9TLR8 | |
| SCHEMBL24424524 | 0.92 | FFAR4 (0.37) | FFAR4FFAR1TBK1TLR9TLR8 | |
| SCHEMBL24424040 | 0.92 | FFAR4 (0.37) | FFAR4FFAR1TBK1TLR9TLR8 | |
| SCHEMBL25090729 | 0.92 | FFAR4 (0.37) | FFAR4FFAR1TBK1TLR9TLR8 | |
| SCHEMBL24423911 | 0.92 | FFAR4 (0.37) | FFAR4FFAR1TBK1TLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522605-A1 | SOLID FORM OF PPAR-GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2025-03-19 | — | — | EP | disclosed |
| CN-119156380-A | Solid crystalline forms of PPAR-gamma modulators and methods of use thereof | 卫材R&D管理有限公司 | 2024-12-17 | — | — | CN | disclosed |
| WO-2023219879-A1 | SOLID FORM OF PPAR-gamma MODULATORS AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-11-16 | — | — | WO | disclosed |
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |