Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 1.00 |
| ▸ | TLR7 | Q9NYK1 | 20/20 | 1.00 |
| ▸ | TLR9 | Q9NR96 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19952696 | 1.00 | TLR8 (1.00) | TLR8TLR7TLR9 | |
| SCHEMBL19952216 | 0.89 | TLR8 (1.00) | TLR8TLR7TLR9 | |
| SCHEMBL29584978 | 0.89 | TLR8 (1.00) | TLR8TLR7TLR9 | |
| SCHEMBL19952303 | 0.89 | TLR9 (1.00) | TLR8TLR7TLR9 | |
| SCHEMBL19952079 | 0.85 | TLR9 (1.00) | TLR8TLR7TLR9 | |
| SCHEMBL29584159 | 0.85 | TLR9 (1.00) | TLR8TLR7TLR9 | |
| SCHEMBL29583606 | 0.85 | TLR9 (1.00) | TLR8TLR7TLR9 | |
| SCHEMBL19952245 | 0.85 | TLR9 (1.00) | TLR8TLR7TLR9 | |
| SCHEMBL29584353 | 0.85 | TLR9 (1.00) | TLR8TLR7TLR9 | |
| SCHEMBL19951763 | 0.85 | TLR9 (1.00) | TLR8TLR7TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109923108-B | Pyridyl-substituted indole compounds | 百时美施贵宝公司 | 2022-04-29 | — | — | CN | claimed |
| CN-109923108-B | Pyridyl-substituted indole compounds | 百时美施贵宝公司 | 2022-04-29 | — | — | CN | disclosed |